TOP
Nav Bar
  1. General Info
  2. Effects Info
  3. Reference
Drug Interaction Details
01. General Information
Pair Name Rosmarinic acid, Anti-MUC1 antibody
Phytochemical Name Rosmarinic acid (PubChem CID: 5281792 )
Anticancer drug Name Anti-MUC1 antibody (PubChem CID: / )
Structure of
Phytochemical
2D-img
Download
2D MOL 3D MOL
Structure of
Anticancer Drug
2D-img
Download
2D MOL 3D MOL
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
Hide/Show
Enhancing Drug Efficacy
Hide/Show
Combination Pair ID: 320
Pair Name Rosmarinic acid, Anti-MUC1 antibody
Disease Info [ICD-11: 2B72] Gastric cancer Investigative
Biological Phenomena Induction-->Apoptosis
Gene Regulation Down-regulation Expression BCL2 hsa596
Down-regulation Expression BCL-xL hsa598
Up-regulation Expression CASP3 hsa836
Up-regulation Expression CASP9 hsa842
Down-regulation Expression LGALS3 hsa3958
Up-regulation Expression MUC1 hsa4582
Up-regulation Expression TP53 hsa7157
In Vitro Model AGS Gastric adenocarcinoma Homo sapiens (Human) CVCL_0139
Result Results of the study indicate that combined action of anti-MUC1 and RA is more effective than monotherapy in relation to examined cancer related factors. Such treatment can be considered as new, promising strategy in gastric cancer therapy.
03. Reference
No. Title Href
1 Anti-cancer effect of combined action of anti-MUC1 and rosmarinic acid in AGS gastric cancer cells. Eur J Pharmacol. 2021 Jul 5;902:174119. doi: 10.1016/j.ejphar.2021.174119. Click
It has been 46641 visits since 2024.08
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang
TOP